Publikationen des Verbundes

2013

Basler T, Brumshagen C, Beineke A, Goethe R, Bäumer W.
Mycobacterium avium subspecies impair dendritic cell maturation.
Innate Immun. 2013 Jan 2. [Epub ahead of print]
PMID: 23283733

Weigoldt M, Meens J, Bange FC, Pich A, Gerlach GF, Goethe R.
Metabolic adaptation of Mycobacterium avium subsp. paratuberculosis to the gut environment.
Microbiology. 2013 Feb;159(Pt 2):380-91. doi: 10.1099/mic.0.062737-0. Epub 2012 Dec 6.
PMID: 23223439

2012

Renz H, Brandtzaeg P, Hornef M.
The impact of perinatal immune development on mucosal homeostasis and chronic inflammation.
Nat Rev Immunol. 2011 Dec 9;12(1):9-23.
22158411

Decker E, Hornef M, Stockinger S.
Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children.
Gut Microbes. 2011 Mar-Apr;2(2):91-8.
21637025

Roderfeld M, Koc A, Rath T, Blöcher S, Tschuschner A, Akineden O, Fischer M, von Gerlach S, Goethe R, Eckelt E, Meens J, Bülte M, Basler T, Roeb E.
Induction of matrix metalloproteinases and TLR2 and 6 in murine colon after oral exposure to Mycobacterium avium subsp. paratuberculosis.
Microbes Infect. 2012 Jan 16. [Epub ahead of print]
22289202

Fritsch I, Luyven G, Köhler H, Lutz W, Möbius P.
Suspicion of Mycobacterium avium subsp. paratuberculosis Transmission between Cattle and Wild-Living Red Deer (Cervus elaphus) by Multitarget Genotyping.
Appl Environ Microbiol. 2012 Feb;78(4):1132-9. Epub 2011 Dec 16.
22179249

2011

Pott J, Mahlakõiv T, Mordstein M, Duerr CU, Michiels T, Stockinger S, Staeheli P, Hornef MW.
IFN-lambda determines the intestinal epithelial antiviral host defense.
Proc Natl Acad Sci U S A. 2011 May 10;108(19):7944-9. Epub 2011 Apr 25.
21518880

Fritsch I, Luyven G, Köhler H, Lutz W, Möbius P.
Suspicion of Mycobacterium avium subsp. paratuberculosis transmission between cattle and wild-living red deer (Cervus elaphus) by multi target genotyping.
Appl Environ Microbiol. 2011 Dec 16. [Epub ahead of print]
22179249

Borrmann E, Möbius P, Diller R, Köhler H.
Divergent cytokine responses of macrophages to Mycobacterium avium subsp. paratuberculosis strains of Types II and III in a standardized in vitro model.
Vet Microbiol. 2011 Aug 26;152(1-2):101-11. Epub 2011 Apr 12.
21555192

Weigoldt, M., Meens, J., Doll, K., Fritsch, I., Möbius, P., Goethe, R., Gerlach, G.-F.
Differential proteome analysis of Mycobacterium avium subsp. paratuberculosis grown in vitro and isolated from cases of clinical Johnes´s disease.
Microbiology 2011 Feb;157(Pt 2):557-65. Epub 2010 Nov 4.
21051485

Rath T, Roderfeld M, Blöcher S, Rhode A, Basler T, Akineden Ö, Abdulmawjood A, Halwe JM, Goethe R, Bülte M, Roeb E.
Presence of intestinal Mycobacterium avium subspecies paratuberculosis (MAP) DNA is not associated with altered MMP expression in ulcerative colitis.
BMC Gastroenterol. 2011 Apr 8;11:34.
21477272

2010

Chassin, C., Kocur, M., Pott, J., Duerr, C.U., Gütle, D., Lotz, M., Hornef, M.W.
miR-146a mediates protective innate immune tolerance in the neonate intestine.
Cell Host Microbe 8: 358-68, 2010.
20951969

Duerr, C.U., Salzman, N.H., Dupont, A., Szabo, A., Henriques Normark, B., Normark, S., Locksley, RM, Mellroth, P., Hornef, M.W.
Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes.
Muc Immunol. 2010 Oct 27 [Epub ahead of print]).
20980996

Dolowschiak, T., Chassin, C., Ben Mkaddem, S., Fuchs, T.M., Weiss, S., Vandewalle, A., Hornef, M.W..
Potentiation of epithelial innate host responses by intercellular communication.
PLoS Pathogens, 2010, 6:e1001194.
21124989

Rath, T., Roderfeld, M., Halwe, J.M., Tschuschner, A., Roeb, E., Graf J.
Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis.
Scandinavian Journal of Gastroenterology, 2010; 45(10):1186-96.
20568971

Roderfeld M, Rath T, Lammert F, Dierkes C, Graf J, Roeb E.
Innovative immunohistochemistry identifies MMP-9 expressing macrophages at the invasive front of murine HCC.
World J Hepatol 2010;(2):175-179.
21160992

Basler T, Holtmann H, Abel J, Eckstein T, Bäumer W, Valentin-Weigand P et al.
Reduced transcript stabilization restricts TNF-{alpha} expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannan.
Journal of Leukocyte Biology 2010;87:173-183.
19850884

2009

Pott J, Basler T, Duerr C. U, Rohde M, Goethe R, Hornef M. W.
Internalization-dependent recognition of Mycobacterium avium ssp. paratuberculosis by intestinal epithelial cells.
Cell Microbiol. 2009;11.
19681906

Möbius P, Fritsch I, Luyven G, Hotzel H, Köhler H.
Unique genotypes of Mycobacterium avium subsp. paratuberculosis strains of Type III.
Vet Microbiol 2009.
19647378

Rath T, Roderfeld M, Graf J, Roeb E.
Matrix metalloproteinases in inflammatory bowel disease – from basic research to clinical significance.
Z Gastroenterol 2009;47:758-769.
19662589

2008

Möbius P, Luyven G, Hotzel H, Köhler H.
High genetic diversity among Mycobacterium avium subsp. paratuberculosis strains from German cattle herds shown by combination of IS900 restriction fragment length polymorphism analysis and mycobacterial interspersed repetitive unit-variable-number tandem.
Journal of Clinical Microbiology 2008;46(3):972-981.
18174306

Roeb E.
In: Matrix Metalloproteinases in „Molecular targets“ of the Encyclopedia of Molecular Pharmacology.
Springer Verlag. 2009.

Heinzmann J, Wilkens M, Dohmann K, Gerlach G.-F.
Mycobacterium avium subsp. paratuberculosis-specific mpt operon expressed in M. bovis BCG as vaccine candidate.
Veterinary Microbiology 2008;130:330-337.
18343053

Basler T, Geffers R, Weiss S, Valentin-Weigand P, Goethe R.
Mycobacterium avium subspecies induce differential of pro-inflammatory mediators in a murine macrophage model: evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis.
Immunbiology 2008;213:879-888.
18926302

Schönenbrücher H, Abdulmawjood A, Failing K, Bülte M.
New Triplex Real-Time PCR Assay for Detection of Mycobacterium avium subsp. paratuberculosis in Bovine Feces. Applied and Environmental Microbiology 2008;74(9):2751-2758.
18326682